FROM PETROLEUM WITH LOVE by Bartłomiej Furman, 26.10.2017
Ruben Martin and co-workers described in Nature a catalytic method that is capable of promoting carboxylation reactions at remote and unfunctionalized aliphatic sites with carbon dioxide at atmospheric pressure. The reaction occurs via selective migration of the catalyst along the hydrocarbon side-chain with excellent regioand chemoselectivity, representing a remarkable reactivity relay when compared with classical cross-coupling reactions.
The authors have shown that raw materials obtained in bulk from petroleum processing, such as alkanes and unrefined mixtures of olefins, can be used as substrates. This offers an opportunity to integrate a catalytic platform en route to valuable fatty acids by transforming petroleum-derived feedstocks directly.