Assistant professor
Young Leader, Head of sub-group IIB

Building: D
Lab: 124/126
Phone.: +4822 343 2124
E-mail: michal.michalak@icho.edu.pl
Education & professional experiances
- M.Sc. in organic chemistry, Faculty of Chemistry, University of Białystok (supervisor: Dr. R. Łaźny, Assoc. Prof.)
2007 - Ph.D. in organic chemistry; Institute of Organic Chemistry, Polish Academy of Sciences, Warsaw, Poland (supervisor: prof. Jerzy Wicha)
2008 - post-doc position at Department of Chemistry and Organic Synthesis, Ecole Polytechnique, Palaiseau, France (Prof. Samir Zard group)
II.2009-III.2010 - Faculty of Chemistry, Warsaw University, Poland (prof. Karol Grela group)
Selected papers
1.Lazny, R. and M. Michalak, Application of piperazine-derived hydrazone linkers for alkylation of solid-phase immobilized ketones. Synlett 2002, 1931-1934.
2.Lazny, R. and M. Michalak, Tools for combinatorial chemistry. Part 2. Linkers used in solid-phase organic synthesis Wiadomości Chemiczne 2003, 57, 1061-1091.
3.Michalak, M., K. Michalak, and J. Wicha, A Facile Synthetic Approach to Cyclopentacyclooctane Diterpenoid Skeleton, Using Ring-Closing Metathesis. Chemickie Listy 2003, 97, 290.
4.Michalak, M. and J. Wicha, Efficient olefin isomerization-ring-closing metathesis reaction in sterically hindered systems: Study on simultaneous use of the Grubbs metathesis and ruthenium hydride isomerization catalysts. Synlett 2005, 2277-2280.
5.Michalak, K., M. Michalak, and J. Wicha, Studies towards the total synthesis of di- and sesterterpenes with dicyclopenta a,d cyclooctane skeletons. Three-component approach to the A/B rings building block. Molecules 2005, 10, 1084-1100.
6.Michalak, K., M. Michalak, and J. Wicha, Studies toward the total synthesis of di- and sesterterpenes with a dicyclopenta a,d cyclooctane skeleton. Construction of a versatile A/B ring building block via a ring-closing metathesis reaction and carbocationic rearrangement. Tetrahedron Letters 2005, 46, 1149-1153.
7.Michalak, K., M. Michalak, and J. Wicha, A synthetic approach to the functionalized hydroazulene core of guanacastepenes and heptemerenes. Tetrahedron Lett. 2008, 49, 6807-6809.
8.Michalak, K., M. Michalak, and J. Wicha, A facile construction of the tricyclic 5-7-6 scaffold of fungi- derived diterpenoids. The first total synthesis of (+/-)- heptemerone G and a new approach to Danishefsky's intermediate for a guanacastepene A synthesis. Tetrahedron Lett. 2010, 51, 4344-4346.
9.Michalak, K., M. Michalak, and J. Wicha, Construction of the Tricyclic 5-7-6 Scaffold of Fungi-Derived Diterpenoids. Total Synthesis of (+/-)-Heptemerone G and an Approach to Danishefsky's Intermediate for Guanacastepene A Synthesis. J. Org. Chem. 2010, 75, 8337-8350.
10.Michalak, M., Ł. Gułajski, and K. Grela, Alkene Metathesis, in Science of Synthesis: Houben-Weyl Methods of Molecular Transformations, A. de Meijere, Editor. 2010, Georg Thieme Verlag KG. p. 327-437.
11.Wang, H., et al., Steric Control of alpha- and beta-Alkylation of Azulenone Intermediates in a Guanacastepene A Synthesis. J. Org. Chem. 2010, 75, 762-766.
12.Leitgeb, A., et al., Unequal siblings: Adverse characteristics of naphtalene-based Hoveyda-type second generation initiators in ring opening metathesis polymerization. Journal of Polymer Science Part A: Polymer Chemistry 2011, 49, 3448-3454.
13.Michalak, M. and J. Wicha, Application of a metathesis reaction in the synthesis of sterically congested medium-sized rings. A direct ring closing versus a double bond migration-ring closing process. Org. Biomol. Chem. 2011, 9, 3439-3446.
14.Michalak, M., et al., A Formal Synthesis of Ezetimibe via Cycloaddition/Rearrangement Cascade Reaction. J. Org. Chem. 2011, 76,  6931-6936.
15.Michalak, M., et al., Synthetic Studies on Dicyclopenta[a,d]cyclooctane Terpenoids: Construction of the Core Structure of Fusicoccins and Ophiobolins on the Route Involving a Wagner-Meerwein Rearrangement. J. Org. Chem. 2011: ASAP.

Institute of Organic Chemistry
Polish Academy of Sciences
Kasprzaka 44/52, 01-224 Warsaw, Poland
phone: +48 22 343 20 53
fax: +48 22 632 66 81
e-mail: bartlomiej.furman@icho.edu.pl
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